5-((5-氯-1H-吡咯并[2,3-B]吡啶-3-基)甲基)-N-((6-(三氟甲基)吡啶-3-基)甲基)吡啶-2-胺
Pexidartinib
CAS: 1029044-16-3
Molecular Formula: C20H15ClF3N5
5-((5-氯-1H-吡咯并[2,3-B]吡啶-3-基)甲基)-N-((6-(三氟甲基)吡啶-3-基)甲基)吡啶-2-胺 - Names and Identifiers
5-((5-氯-1H-吡咯并[2,3-B]吡啶-3-基)甲基)-N-((6-(三氟甲基)吡啶-3-基)甲基)吡啶-2-胺 - Physico-chemical Properties
| Molecular Formula | C20H15ClF3N5 |
| Molar Mass | 417.8148 |
| Density | 1.458±0.06 g/cm3(Predicted) |
| Solubility | DMSO: ≥ 30 mg/mL |
| Appearance | Form solid, color White |
| pKa | 12.81±0.40(Predicted) |
| Storage Condition | -20°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
| Physical and Chemical Properties | Bioactive Pexidartinib (PLX3397) is an orally effective multi-target CSF-1R,Kit (c-Kit), and FLT3 receptor tyrosine kinase inhibitor with IC50 of 20 nM, 10 nM, and 160 nM, respectively. Pexidartinib (PLX3397) can induce apoptosis and necrosis and has antitumor activity. Phase 3. |
5-((5-氯-1H-吡咯并[2,3-B]吡啶-3-基)甲基)-N-((6-(三氟甲基)吡啶-3-基)甲基)吡啶-2-胺 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.393 ml | 11.967 ml | 23.934 ml |
| 5 mM | 0.479 ml | 2.393 ml | 4.787 ml |
| 10 mM | 0.239 ml | 1.197 ml | 2.393 ml |
| 5 mM | 0.048 ml | 0.239 ml | 0.479 ml |
Last Update：2024-01-02 23:10:35
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Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
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Product Name: PLX-3397 Visit Supplier Webpage Request for quotationCAS: 1029044-16-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Pexidartinib (PLX3397) Visit Supplier Webpage Request for quotationCAS: 1029044-16-3
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Spot supply
Product Name: Pexidartinib Visit Supplier Webpage Request for quotationCAS: 1029044-16-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Pexidartinib Visit Supplier Webpage Request for quotationCAS: 1029044-16-3
Tel: 18301782025
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5-((5-氯-1H-吡咯并[2,3-B]吡啶-3-基)甲基)-N-((6-(三氟甲基)吡啶-3-基)甲基)吡啶-2-胺
Dexamethasone Sodium Phosphate
17A-羟基黄体酮醋酸酯(单脂)
洋川芎内酯F
对溴苄胺盐酸盐
1-溴芘(2-GDP-1)
法罗培南(钠)(二倍半水合物)
3-氟吡啶-4-硼酸
4-溴-1H-吡唑-3-羧酸乙酯
Transparent Yellow G
Dexamethasone Sodium Phosphate
17A-羟基黄体酮醋酸酯(单脂)
洋川芎内酯F
对溴苄胺盐酸盐
1-溴芘(2-GDP-1)
法罗培南(钠)(二倍半水合物)
3-氟吡啶-4-硼酸
4-溴-1H-吡唑-3-羧酸乙酯
Transparent Yellow G